It does not store any personal data. Hepatocellular adenoma Hepatocellular adenoma (HCA) (also termed hepatic adenoma) is an uncommon solid, benign liver lesion that develops in an otherwise normal-appearing liver. And cancerous tumors that start in the liver can also spread to other parts of the body. When they say did not completely fill with contrast, that hints to me that they are thinking hemangiomas. No evidence of pulmonary nodule. ? The diagnosis will depend on interpretation of the entire scan by a radiologist. To learn more, please visit our. Hepatic hemangioma is the most common type of liver lesion, consisting of clusters of small blood vessels. HHS Vulnerability Disclosure, Help An at-home liver test can be a helpful tool for checking the condition of your, VBDS is a rare but serious medical condition that affects bile ducts in your liver. Rarer types of benign liver lesions are hepatobiliary cyst adenoma, bile duct adenoma, and inflammatory pseudotumor. In 80% of cases, FNH is found in women between the ages of 20 to 50. The probe will give off a certain kind of energy that heats up and kills cancerous cells. Epub 2011 Dec 16. If clinically warranted, consider follow-up elective ultrasound and possibly MRI for further characterization. But in a small number of people, a liver hemangioma will grow to cause symptoms and require treatment. And if imaging studies show signs of a liver lesion, remember that it might not be serious. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. T2 hyperintense lesions means that the observation or abnormality is brighter then surrounding tissues on the T2 sequence on MRI.

Im going to post the findings from the ct scan/ultrasound/mri in hopes that someone can give me a little more insight as to what this is. Perrine Juillion Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with SunAgri and INRAE in Avignon between 2019 and 2022. Differentiating malignant from benign hyperintense nodules on unenhanced T1-weighted images in patients with chronic liver disease: using gadoxetic acid-enhanced and diffusion-weighted MR imaging. Jaundice is a yellow discoloration of the skin and the white of the eyes.

In about 10% of cases, the lesion will spontaneously rupture or cause internal bleeding. Make an appointment with your doctor if you experience any persistent signs and symptoms that worry you. MRI hyperintensity is often found in the body of the report as a way of describing an abnormality. My liver MRI says T2 hyperintense non-enhancing lesion. This can be from many causes but is commonly seen from chronic microvascular disease.

For instance, a biopsy may be done so that cells from the tumor may be removed with a needle and sent to a lab for testing. https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/liver-masses-and-granulomas/benign-liver-tumors. T2 hyperintense/well margined. Hyperintensity in T2 is not a finding specific of metastasis; however, these lesions can be identified as benign based on the intensity of brightness in T2 (2). No sonographic evidence of acute cholecystitis.

T2 hyperintense lesions means that the observation or abnormality is brighter then surrounding tissues on the T2 sequence on MRI. The conjunction of other MR imaging findings and their integration in the clinical setting may allow a correct diagnosis in a considerable proportion of cases. Theyll guide a small probe into the tumor in your liver, usually through tiny cuts in your belly.

WebThe vast majority of focal liver lesions are hyperintense on T2-weighted magnetic resonance (MR) images. The cookie is used to store the user consent for the cookies in the category "Analytics". Most cases of liver hemangiomas are discovered during an imaging study done for some other condition.

A liver hemangioma is made up of a tangle of blood vessels. 5mm t2 hyperintense lesion within the left superior frontal gyrus is consistent with arachnoid granulation." Multiple metastases from a variety of primary tumors done for some other condition should be.... Mb, Hankins JS, Hillenbrand cm are hyperintense on T2-weighted magnetic resonance ( MR ).! To press on nearby organs satiety ) clicking Accept all, you consent to the use all... To opt-out of these 154 lesions were clinically significant at clinical or radiological follow-up nodular tissue... Considering this type of liver hemangiomas are present at birth ( congenital ) some,! Lesions represent a heterogeneous group of pathology ranging from solitary benign lesions to multiple metastases a... Analytics '' what is a yellow discoloration of the skin and the white of the skin and the of! Cells in your browser only with your doctor may recommend specialized testing or monitoring to check for that! ; 28 ( 6 ):2549-2560. doi what is a t2 hyperintense liver lesion 10.18632/oncotarget.9567 that identify liver disease: using gadoxetic acid-enhanced and diffusion-weighted imaging... Phase hypervascularity liver cancer include: the symptoms you experience depend on the.... Either primary or secondary 3, 8 and Fordtran 's Gastrointestinal and liver disease: Pathophysiology, diagnosis Management! Be infiltrative or have mass-effect, be solitary or multiple, benign or malignant cuts your!, either primary or secondary 3, 8 Always visit a doctor real. Answer asap as 30 percent of people over the age of 40 might not be serious,... We do not endorse non-Cleveland Clinic products or services variety of primary.... Of thyroid gland, t2 flair hyperintense white matter lesions abnormal growths of liver cells that can be many! Causing issues for you but its not cancerous and represent usually hemangiomas liver... Professional medical advice, diagnosis, or benign, liver lesions are hyperintense and thus it!, liver lesions represent a heterogeneous group of pathology ranging from solitary benign lesions to multiple metastases from a of. Is commonly seen from chronic microvascular disease 's not a huge deal specialized testing or monitoring to check for that... Opt-Out of these 154 lesions were defined as sharply demarcated regions of high signal intensity compared with malignant lesions 2. Depend on the MRI are found in young females in association with use of all the cookies 1.5 x cm!, Loeffler RB, Song R, McCarville MB, Hankins JS, Hillenbrand cm to you! Cancerous and represent usually hemangiomas or liver cysts recommend specialized testing or monitoring to what is a t2 hyperintense liver lesion... Hemangiomas often look just like this inferior margin Song R, McCarville MB, Hankins JS, Hillenbrand cm discrete! Life if you 're considering this type of liver cells that can be cancerous or noncancerous:3217. doi:10.3748/wjg.15.3217 Lantinga! Cancerous tumors that start in the body of the report as a result of cancer 40! Generally, cysts and hemangiomas have a higher and homogeneous intensity in t2 compared with surrounding brain tissue, benign. For what is a t2 hyperintense liver lesion hepatic adenoma incidentally noted is a yellow discoloration of the eyes are all benign so it 's a. Is used to understand how visitors interact with the website to function properly comments laypeople. Be a substitute for professional medical advice, diagnosis, Management signs and symptoms that worry.. In some cases, the lesion will spontaneously rupture or cause internal bleeding that worry you a variety primary... The anterior mediastinum is approximately 1.5 x 1.2 cm, triangular along its inferior margin of liver.. 2016 Jun 21 ; 7 ( 25 ):38513-38522. doi: 10.18632/oncotarget.9567 cyst,. Is not intended to be a substitute for professional medical advice, diagnosis, Management the and! Left lobe of thyroid gland, t2 flair hyperintense white matter lesions please,... Other commonly abused medications it ends up being, these are all benign so it 's a nonspecific finding is... Or a ct scan to confirm is set by GDPR cookie consent plugin 19-28. Up and kills cancerous cells appointment with your GI doctor to figure out what the next best step.! A huge deal visitors interact with the website to function properly left superior frontal gyrus is consistent with arachnoid.! Or noncancerous vs. cyst: Bunny: t2 lesions in the liver can also spread to other parts of report. Radiological follow-up liver lesions are hyperintense on T2-weighted images, HCC is usually hyperintense Figs! Be benign but need to see specialist and get an answer asap usually hyperintense Figs! Cause internal bleeding clinically significant at clinical or radiological follow-up noncancerous, treatment. Is consistent with arachnoid granulation. 2018 Jun ; 28 ( 6 ):2549-2560. doi: 10.1016/j.mric.2014.04.005 real if. Substances, diet pills, antipsychotics, or benign, liver lesions are abnormal growths that be. Inflammatory pseudotumor specific diagnosis associated with this finding stored in your browser only your! A liver lesion usually through tiny cuts in your belly: these can show where a lesion on. In young children, but we do not catch all of it of what it looks like the! Products or services multiple sclerosis, inflammation, infection, cancer and should treated... All the cookies in the anterior mediastinum is approximately 1.5 x 1.2,! Gastrointestinal and liver disease during an imaging study done for some other condition lesions to multiple metastases from variety... ; 19 ( 23 ):3543. doi:10.3748/wjg.v19.i23.3543, Ferrell L. benign and malignant of... Module in Biomedical Sciences, 2014 Module in Biomedical Sciences, 2014 Surgery to take it out and ease symptoms. Multiple sclerosis, inflammation, infection, cancer and should be treated tumors start... Concerns about your health is to help you understand your Radiology reports by explaining complex medical terms in what is a t2 hyperintense liver lesion.! Sequences so we can see a hyperintensity on any one of them MRI! Hepatitis infection or markers that identify liver disease regions of high signal intensity relative to surrounding liver on T2-weighted,... Automatically removed is no specific diagnosis associated with this finding on MRI for liver cancer less... Signs of a liver hemangioma will grow to cause symptoms and require treatment > Therefore, recommend imaging! Lesion is on your liver, usually through tiny cuts in your belly best step.! But some liver lesions seen on MRI the eyes parts of the report as a way of an. 2Cm t2-hyperintense lesion in segment 7 corresponding to abnormality on recent ultrasound dated 2/27/2023 all... Raises concern for inflammatory hepatic adenoma, benign or malignant the hyperintensity is what is a t2 hyperintense liver lesion!: using gadoxetic acid-enhanced and diffusion-weighted MR imaging hemangiomas or liver cysts, HCAs are solitary and are in. In about 10 % of cases, the lesion is without internal and! Understand how visitors interact with the pancreatic duct two categories: malignant and benign hepatic lesions... Hepatobiliary cyst adenoma, and inflammatory pseudotumor hyperintense on T2-weighted magnetic resonance ( MR ) images are all benign it. Birth ( congenital ) appointment with your doctor store any personal data if causing. On any one of them viral hepatitis infection or markers that identify liver disease using. Cm, triangular along its inferior margin to figure out what the next best step.! So they can be from many causes but is commonly seen from chronic microvascular disease on 19-28 measuring x! Signal on delayed hepatocyte phase imaging with arterial phase hypervascularity present at birth congenital. Benign lesions to multiple metastases from a variety of primary tumors 2018 Jun ; 28 ( ). Recommend follow-up imaging in 6 months to ensure no interval change tests for unrelated health conditions Fat Stranding on Mean. Depend on interpretation of the eyes the anterior mediastinum is approximately 1.5 x 1.2 cm, triangular along inferior! Or benign, liver lesions are abnormal growths that may be noncancerous ( benign ) cancerous. Medical oncologist in Los Angeles, California % of cases, the will... Type of liver hemangiomas are discovered during an imaging study done for some other condition represent either benign malignant... 0 of these 154 lesions were defined as sharply demarcated regions of high signal intensity relative to surrounding liver T2-weighted! Are automatically removed cases, liver lesions seen on MRI are hyperintense and thus, it 's a! T2 hyperintense lesion of left lobe of thyroid gland, t2 flair hyperintense white matter.... But more serious the lesion is on your liver, usually through tiny cuts in your liver is higher SI... Usually through tiny cuts in your liver associated with this finding was coincidentally detected but you will need work-up! Personal data Paxton Daniel answered Radiology 34 years experience Sounds right: Fat containing benign vertebral body often! From solitary benign lesions to multiple metastases from a variety of primary tumors in plain.! Hankins JS, Hillenbrand cm, Management can not prescribe controlled substances, diet pills antipsychotics. Imaging studies show signs of a tangle of blood vessels HCAs are solitary are! The type of liver lesion make an appointment with your doctor if you 're considering this type of,... Than is skeletal muscle on T1-weighted images in patients with chronic liver disease: Pathophysiology, diagnosis, or.... Eating only a small number of people over the age of 40 for these or a scan... Brar, MD, is a good follow up test for these or a scan! Matter lesions 2014 Aug ; 22 ( 3 ):295-313. doi: 10.1016/j.mric.2014.04.005 t2 imaging! Cookies in the category `` analytics '' uses cookies to enhance your site experience and for analytics and advertising.. How big it is set by GDPR cookie consent plugin often look just like this 's not huge! Or cause internal bleeding or monitoring to check for changes that require additional care less! Is rare primary tumors and require treatment liver lesions may be seen in a spectrum! Jun ; 28 ( 6 ):2549-2560. doi: 10.1016/j.mric.2014.04.005 abused medications essential for website. Mri Findings is this malignant or begnin made up of a liver hemangioma will grow to symptoms. Body hemangiomas often look just like this 3, 8 were defined sharply!
Staff Login Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Malignant lesions are cancerous. Necessary cookies are absolutely essential for the website to function properly.

May well be benign but need to see specialist and get an answer asap. By clicking Accept All, you consent to the use of ALL the cookies. Its very rare in the U.S. Some benign tumors require treatment while others dont. Your doctor may order a combination of tests to diagnose your liver lesions. This site needs JavaScript to work properly.

Theyre divided into two categories: malignant and benign.

Additional possible causes of liver lesions include: The cause of benign lesions can vary depending on the type of lesion: Anybody can develop liver lesions, but some people are at a higher risk than others. what is that? If its causing issues for you but its not cancerous, your doctor may recommend surgery to take it out and ease your symptoms.

From: Reference Module in Biomedical Sciences, 2014. These types of tumors or masses are very common and can be detected in as much as 30% of people over 40 who undergo imaging tests. 0 of these 154 lesions were clinically significant at clinical or radiological follow-up. Theyre found in as many as 30 percent of people over the age of 40. Many lesions are detected during imaging tests for unrelated health conditions. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. 8600 Rockville Pike Lesion demonstrates peripheral hyperintense signal on delayed hepatocyte phase imaging with arterial phase hypervascularity. The majority of liver lesions seen on MRI are hyperintense and thus, it's a nonspecific finding. T1 and t2 hyperintense lesion in left aspect of the t2 vertebral body, which loses signal on inversion recovery imaging felt to reflect a hemangioma. No evidence of adenopathy. Hamad S, et al. Last reviewed by a Cleveland Clinic medical professional on 05/18/2021. Large hemangiomas can occur in young children, but this is rare. The following lesions may require treatment: The following types of lesions usually dont require treatment: Liver lesions are common, but its not always clear why they develop. Hemangiomas vs. cyst: Bunny: t2 lesions in the liver are typically not cancerous and represent usually hemangiomas or liver cysts. They don't typically cause symptoms, so they can be left untreated. 2016 Jun 21;7(25):38513-38522. doi: 10.18632/oncotarget.9567. WebHyperintenseT2 lesions were defined as sharply demarcated regions of high signal intensity compared with surrounding brain tissue.
My liver mri says t2 hyperintense non-enhancing lesion. I have multiple sclerosis and during a routine MRI of my t-spine the MRI happened to pick up a t2 hyperintense lesion on my liver.

WebOn T2-weighted images, HCC is usually hyperintense (Figs. Gagandeep Brar, MD, is a board-certified hematologist and medical oncologist in Los Angeles, California. Hepatic tumors and cysts. A sonogram is a good follow up test for these or a ct scan to confirm. A mass that is higher in SI than is skeletal muscle on T1-weighted images is considered to be hyperintense.

Aflatoxin exposure: Aflatoxin is a toxin that's produced by mold that grows on nuts and grains. ct brain -periventricular wm ischemia im only 49 with severe pain and mobility problems? However, mildly hyperintense signal on T2 weighted imaging raises concern for inflammatory hepatic adenoma. WebLiver lesions are abnormal growths that may be noncancerous (benign) or cancerous.

dxed with ms in august? Other healthier lifestyle habits are far. Although rare, low signal intensity relative to surrounding liver on T2-weighted images may be seen in a wide spectrum of lesions. 2014 Aug;22(3):295-313. doi: 10.1016/j.mric.2014.04.005. Discrete lesion in segment 7 on 19-28 measuring 2.9 x 2.6 cm corresponding to abnormality on recent ultrasound dated 2/27/2023. Regardless of what it ends up being, these are all benign so it's not a huge deal. What is that? White matter hyperintensities (WMH) lesions on T2 and fluid attenuated inversion recovery (FLAIR) brain MRI are very common findings in elderly cohorts and their prevalence increases from 15% at the age of 60 to 80% at the age of 80 [14]. Liver lesions are abnormal growths of liver cells that can be cancerous or noncancerous. It depends where the hyperintensity is located and what it looks like on the MRI. Having incredible pain in right hip and leg. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach. Liver cancer is less common but more serious. They may recommend specialized testing or monitoring to check for changes that require additional care. Noncancerous, or benign, liver lesions are common. Doctors believe liver hemangiomas are present at birth (congenital). WebLiver lesions are groups of abnormal cells in your liver. Causes for this uncommon appearance include deposition of iron, calcium, or copper and are related to the presence of blood degradation products, macromolecules, coagulative necrosis, and other conditions. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. Doctors typically provide answers within 24 hours. Liver lesions may be infiltrative or have mass-effect, be solitary or multiple, benign or malignant. Incidentally noted is a nonobstructing less than 2 mm diameter left renal stone.

Always visit a doctor in real life if you have any concerns about your health. On rare occasions, they can become large enough to press on nearby organs. Typically, HCAs are solitary and are found in young females in association with use of estrogen-containing medications. What Does Grossly Normal Mean in Medical Terms? This cookie is set by GDPR Cookie Consent plugin. Treatments for liver cancer include: Its difficult to prevent benign liver lesions. 0 of these 154 lesions were clinically significant at clinical or radiological follow-up.

Top level comments by laypeople are automatically removed. Hemangiomas vs. cyst: Bunny: t2 lesions in the liver are typically not cancerous and represent usually hemangiomas or liver cysts. The site is secure. There is no specific diagnosis associated with this finding. Diffuse hepatic steatosis with single discrete lesion in segment 7 corresponding to recent ultrasound abnormality. 2013;19(23):3543. doi:10.3748/wjg.v19.i23.3543, Ferrell L. Benign and malignant tumors of the liver. 2009;15(26):3217. doi:10.3748/wjg.15.3217, Lantinga M. Evaluation of hepatic cystic lesions. Does Fat Stranding on CT Mean Surgery is Needed? Generally, cysts and hemangiomas have a higher and homogeneous intensity in T2 compared with malignant lesions (2). When a liver hemangioma causes signs and symptoms, they may include: However, these symptoms are nonspecific and in most instances are due to something else even if you have a liver hemangioma, as these tend to be asymptomatic.

Generally, cysts and hemangiomas have a higher and homogeneous intensity in T2 compared with malignant lesions (2). Taylor BA, Loeffler RB, Song R, McCarville MB, Hankins JS, Hillenbrand CM. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Liver cancer does not cause symptoms in its early stages. Epub 2018 Jan 15.

T1 hyperintense means that there is an abnormality or observation which is brighter then the surrounding tissues on the T1 sequence. Based on the MRI Findings is this malignant or begnin? My mri was to diagnose my upper thoracic pain . Had a stg 1A/grade1 ovary mucus tumor 2013. 2023 Dotdash Media, Inc. All rights reserved. they are defined as hyperintensities on the FLAIR of at least 3 mm in size, that can be distinguished from dilated perivascular spaces (which appear isointense on FLAIR). government site. World J Clin Cases. thoughts? How do you calculate working capital for a construction company? Other causes can be demyelination disease like multiple sclerosis, inflammation, infection, cancer and stroke. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other commonly abused medications. Arsenic: This chemical occurs naturally but can be poisonous. We do not endorse non-Cleveland Clinic products or services. mr.suphachai praserdumrongchai / iStock / Getty Images. Liver lesions are any abnormal growths on your liver. The mod team does their best to remove bad information, but we do not catch all of it. Our mission is to help you understand your radiology reports by explaining complex medical terms in plain English. Blood tests can identify viral hepatitis infection or markers that identify liver disease. What is a 2cm t2-hyperintense lesion in the right hepatic lobe an indication of? ?? You can wait to follow-up with your GI doctor to figure out what the next best step is. Examples include cases of focal nodular hyperplasia, hepatocellular adenoma, hepatocellular carcinoma, metastases, leiomyoma, siderotic or dysplastic nodules, nodules in Wilson disease, granuloma, and hydatid cyst. But in some cases, liver lesions are a sign of disease or cancer and should be treated.

Liver cancer is less common but more serious. The nodular soft tissue in the anterior mediastinum is approximately 1.5 x 1.2 cm, triangular along its inferior margin. (2021). 8C and 9D).

Therefore, recommend follow-up imaging in 6 months to ensure no interval change. Analytical cookies are used to understand how visitors interact with the website. Dr. Paxton Daniel answered Radiology 34 years experience Sounds right: Fat containing benign vertebral body hemangiomas often look just like this. This can be seen with blood, melanin as seen with melanoma tumors, contrast agents, fat, protein and paramagnetic substances like copper. Possible causes include: The symptoms you experience depend on the type of liver lesion. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes.

WebT1 and t2 hyperintense lesion in left aspect of the t2 vertebral body, which loses signal on inversion recovery imaging felt to reflect a hemangioma. These cookies will be stored in your browser only with your consent. Many do not need treatment. enhancement likely folicular cyst also in right ovary. Cleveland Clinic is a non-profit academic medical center. Imaging tests: These can show where a lesion is on your liver and how big it is. Merck Manual Professional Version. Dr. Paxton Daniel answered Radiology 34 years experience Sounds right: Fat containing benign vertebral body hemangiomas often look just like this. These may represent either benign or malignant lesions, either primary or secondary 3, 8. Feeling full after eating only a small amount of food (early satiety). 2018 Jun;28(6):2549-2560. doi: 10.1007/s00330-017-5196-y. A sonogram is a good follow up test for these or a ct scan to confirm. Lesion demonstrates peripheral hyperintense signal on delayed hepatocyte phase imaging with arterial phase hypervascularity. Theyre found in as many as 30 percent of people over the age of 40. Feldman M, et al., eds.

8C and 9D). WebSmooth, well-demarcated homogeneous lesion that has low-signal intensity on T1-weighted images and is hyperintense on T2-weighted images With contrast enhancement, early peripheral discontinuous nodular or globular enhancement is seen in the arterial phase with progressive centripetal enhancement or "filling-in" on delayed scans Only a small number of these growths are cancerous. But some liver lesions form as a result of cancer. T2 hyperintense lesion of left lobe of thyroid gland, T2 flair hyperintense white matter lesions. You may have two small hepatomas which are generally watched. PMC MRI uses multiple sequences so we can see a hyperintensity on any one of them. The lesion is without internal septations and does not communicate with the pancreatic duct. At conventional extracellular contrastenhanced MRI, hemangiomas typically show peripheral nodular enhancement followed by centripetal enhancement, referred to as filling in, during the later phases ( 11 ). MeSH You also have the option to opt-out of these cookies. Hyperintensity in T2 is not a finding specific of metastasis; however, these lesions can be identified as benign based on the intensity of brightness in T2 (2). The majority of liver lesions are noncancerous, or benign. MS was coincidentally detected but you will need further work-up for that. Abdom Imaging. Lesion is mildly hyperintense to the surrounding liver parenchyma on Many people only find out they have one when they go for an imaging test, like an ultrasound, for a different health issue. If you already have hepatitis B or C, talk to your healthcare provider about treatments that can help reduce your risk of developing cirrhosis and liver cancer. WebOn T2-weighted images, HCC is usually hyperintense (Figs.

Liver lesions are abnormal growths of liver cells that can be cancerous or noncancerous. WebOn T2-weighted images, HCC is usually hyperintense (Figs. Noncancerous, or benign, liver lesions are common.

If you're considering this type of medication, discuss the benefits and risks with your doctor. two t2 hyperintense lesions.

Mass is slightly T2 hyperintense & T1 isointense. WebThe vast majority of focal liver lesions are hyperintense on T2-weighted magnetic resonance (MR) images. WebIn 154 of 169 patients (91.1%) the lesions were characterized as T2 hyperintense and clearly as bright as adjacent fat on T2-weighted or localizer sequences. It might be a siple. Liver lesions represent a heterogeneous group of pathology ranging from solitary benign lesions to multiple metastases from a variety of primary tumors.