The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Consult the product instructions and your pharmacist for storage details. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Low blood pressure. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Any long-term side effects/dangers from iron infusions? Keep all regular medical and laboratory appointments. . Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Its caused by your body not having enough iron, which is needed to make hemoglobin. Iron sucrose can also be mixed in a. The insurance company will review the prior authorization request and decide if the drug will be covered. Renal elimination is negligible. These lists dont include all possible side effects. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Your doctor will determine the best dosage to fit your needs. Source: Wolters Kluwer Health. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). After the infusion, you can drive yourself home and return to your usual activities. Do not double the dose to catch up. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Learn about uses, cost, how it works, and more. Learn more about these, as well as the symptoms, diagnosis, and treatments. If these effects continue or worsen, tell your doctor. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. These are not all the side effects that may occur; contact your healthcare provider if you have questions. This is not a list of all drugs or health problems that interact with this medicine. Fortunately, knowing how longside effectslast can help those suffering know what to donext. The drug helps increase your hemoglobin level back to a value thats within the normal range. 4 0 obj You will need to talk about the benefits and risks to you and the baby. Other drugs are available that can treat iron deficiency anemia (IDA). I had Venofer infusions, 2 rounds now in the span of three years. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). No, you most likely wont take Injectafer long term. This gives a total cumulative dose of 1,500 mg of Injectafer. If you have questions about side effects, call your doctor. Then the study was split into the following two groups, which are discussed below. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Understanding what thoseside effectsare can lead to a strategy to prevent them. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. endobj If your symptoms or health problems do not get better or if they become worse, call your doctor. Also tell them about any vitamins, herbs, and supplements you use. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. I used to get a different type but my . Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (IV iron is absorbed by the body more rapidly than oral iron.) How is Venofer (iron sucrose) given? Venofer is not for treating other forms of anemia not caused by iron deficiency. (A medication class is a group of medications that work in a similar way.). Its because everyones body is different. There are 2 tests that your doctor will likely
Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Your healthcare provider will watch you closely for 30 minutes after each dose. pain or burning at the injection site. Brand-name medications usually cost more than generics. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Check with your pharmacist. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. cough. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Pain in your limbs. Injectafer is approved to treat iron deficiency anemia (IDA). If either is present, do not use the liquid. This information is not specific medical advice and does not replace information you receive from the healthcare provider. However, consuming large amounts of alcohol can actually cause anemia in some people. Call your doctor for instructions if you miss an appointment for your Venofer injection. Iron infusion side effects vary depending on which form is being used. Its not known how often people taking a treatment other than Injectafer had diarrhea. (A class of medications describes a group of drugs that work in the same way.). Does Venofer Vial interact with other drugs you are taking? For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Talk with the doctor. (A medication class describes a group of drugs that work in the same way.). Mild side effects of Injectafer can include:*. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Follow your doctor's directions carefully. % Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. For example: Say you weigh 105 pounds (about 48 kilograms). Boxed warnings alert doctors and patients about drug effects that may be dangerous. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Many patients with kidney disease cannot get enough iron from food and require injections. And this could lead to weight gain, if they increase their food intake. Procedure Details Side effectsare uncomfortable reactions to medications or drugs. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. But keep in mind that in this study, delayed allergic reaction only occurred in one person. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Youll receive doses of Injectafer from a healthcare professional at a medical facility. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing In clinical trials,. Most people do not know how long theirside effectswill last until they go through them. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. With this condition, you also have a low hemoglobin level. IQVIA [NSP Audit from MAT November 2013 to November 2018]. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. administered at your doctors office or an infusion center. Feraheme also comes as a liquid thats given by IV infusion. Many people using this medication do not have serious side effects. It can also cause skin irritation and redness. endobj This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. 3 0 obj You may report side effects to the FDA at 1-800-332-1088. Use of the term female in this article refers to sex assigned at birth. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. So you wont pick up this medication from a pharmacy. 5 0 obj It is important to get each dose of this medication as scheduled. This is only a brief summary of general information about this medicine. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Follow all instructions closely. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Data on file, American Regent, Inc. 1. Pain, swelling, or redness at the injection site may occur. Learn about the causes, symptoms, diagnosis, and treatment of this. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. A lack of iron can lead to iron deficiency anaemia if left untreated. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Call your doctor for medical advice about side effects. People with IDA have low blood levels of hemoglobin. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. This includes your doctors, nurses, pharmacists, and dentists. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. You will be watched closely by your doctor for 30 minutes after each dose. Weight changes may be due to symptoms of anemia improving. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. There are currently no generic forms of either drug. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. endobj signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Side effects from HRT depend on a number of factors: The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Depending on your doctors instructions and
The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Why is the range so wide? During Injectafer treatment, your doctor will likely order blood tests. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. If you notice other effects not listed above, contact your doctor or pharmacist. Side effectswill last a very long time if the cause of them is not resolved. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. <> Its FDA-approved to treat iron deficiency anemia (IDA) in adults. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. Very bad and sometimes deadly allergic side effects have rarely happened. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. For more information about Injectafers approved uses, see the section Injectafer uses below. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Hemoglobin is a protein thats found inside your red blood cells. Hemoglobin is a protein thats found in your RBCs. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Blood tests may be needed to check for unwanted effects. Injectafer should be stored between 68F to 77F (20C to 25C). 2005 - 2023 WebMD LLC. Potential injection site discoloration has happened. What are the side effects of Venofer? And these two doses need to be separated by at least 7 days. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor.